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Other ECT agents, such as doxorubicin, 5-fluorouracil, gemcitabine, mitomycin C, and calcium, are also being introduced to the field (37)

13a, Supplementary Table 9), suggesting that the distinct rotamer orientation of H296 ECL2 in Cagri-bound CTR (to accommodate the Glu linker) and/or the observed more open ECL3 conformation induced by the lipidated peptide may facilitate or stabilize an active CTR conformation (Supplementary Fig

07 Site nodule or irritation Rotate to a fresh quadrant for several sessions, inspect the syringe-and-needle technique, and slow the injection